Ammonia → HCID 67499901, compound

HRID 661359Notes

Reaction equation

HRID 661359 reaction equation
[F:1][C:2]1[C:3]([C:8]2([F:18])[CH2:17][CH2:16][C:11]3(OCC[O:12]3)[CH2:10][CH2:9]2)=[N:4][CH:5]=[CH:6][CH:7]=1.ClC1C(C2(F)CCC3(OCCO3)CC2)=NC=CC=1.N>>[F:18][C:8]1([C:3]2[C:2]([F:1])=[CH:7][CH:6]=[CH:5][N:4]=2)[CH2:9][CH2:10][C:11](=[O:12])[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 67499172HCID 67499172, compoundHCID 67499484HCID 67499484, compound

Product 1

HCID 67499901HCID 67499901, compound

Procedure

The title compound was prepared using the procedure as described in Example 1C, except for substituting the product of Example 15B for the product of Example 1B. 1H NMR (300 MHz, DMSO-d6) δ 8.41 (m, 1H), 7.80 (m, 1H), 7.56 (m, 1H), 2.80-2.22 (m, 8H). MS (DCI/NH3) m/e 212 (M+H)+.

Sources & evidence

ORD record
ord-81b32c54ce774a79abe4160314a109ac
Source dataset
uspto-grants-2011_12
Patent number
US08084616B2

Reaction notes

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