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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 661495Generated: November 2, 2026

2-Morpholinoethylamine → 2-methyl-N-(2-morpholinoethyl)-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamide

https://huagongshe.com/reaction/661495

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MorpholinoethylamineHCID 408285—
ReactantHCID 59376005HCID 59376005—
Product2-methyl-N-(2-morpholinoethyl)-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamideHCID 5937604882%

Reaction Steps

Similar procedure as Example 2, 2-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (S4) 0.2 g (1.0 mmol) and 2-morpholinoethanamine 0.27 g (2.1 mmol) was reacted to give 0.25 g (82%) of the titled compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084621B2
Source datasetuspto-grants-2011_12
ORD IDord-4bfbbdffa1a2431ab0764931c1d3c952
Source noteuspto-grants-2011_12