反应详情

The diisopropyl-(benzylthio)-terephthalate obtained in Preparation 2 is refluxed with 500 ml. of methanol, 25 g. of potassium hydroxide and 50 ml. of water for 2 hours. The reaction mixture is then concentrated to a small volume, cooled, diluted with water and filtered through diatomaceous earth (Celite). The thus-obtained filtrate is acidified with 4N hydrochloric acid and the precipitate with forms is collected by filtraton and dried in an oven at 90°-100° C. to yield 45 g. (yield 87%) of (benzylthio)-terephthalic acid having a melting point of 299°-300° C.

1. temperatureis refluxed with 500 ml
2. concentrationThe reaction mixture is then concentrated to a small volume
3. temperaturecooled
4. additiondiluted with water
5. filtrationfiltered through diatomaceous earth (Celite)
6. customthe precipitate with forms is collected by filtraton
7. customdried in an oven at 90°-100° C.
8. customto yield 45 g