2-(2-Ethoxy-2-phenyl-ethenyl)-1-pyrroline tetrafluoroborate → 2-[2-(Isopropylimino)-2-phenylethylidene]-pyrrolidine
Reaction equation
C(O[C:4]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:5][C:6]1[CH2:10][CH2:9][CH2:8][N:7]=1)C.F[B-](F)(F)F>C(N)(C)C>[CH:6]([N:7]=[C:4]([C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH:5]=[C:6]1[CH2:10][CH2:9][CH2:8][NH:7]1)([CH3:10])[CH3:5]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
By refluxing the solution of 9.1 g (0.03 mole) of 2-(2-ethoxy-2-phenyl-ethenyl)-1-pyrroline-tetrafluoroborate in 30 ml of isopropylamine for 1 hour and processing analogously to Example 1, there is obtained crude 2-[2-(isopropylimino)-2-phenylethylidene]-pyrrolidine. The crude base is dissolved in isopropanol, and 2.8 g of methanesulphonic acid is added, whereupon 2-[2-(isopropylimino)-2-phenyl-ethylidene]-pyrrolidine-(1:1)-methanesulphonate, m.p. 175°-176° (decomposition) crystallises out.
Sources & evidence
- ORD record
- ord-6372b588c46e48e2970c30d8d7b3658c
- Source dataset
- uspto-grants-1978_12
- Patent number
- US04130652
Reaction notes
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