HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → 2-[2-Phenyl-2-(diethylamino)-ethenyl]-3,4,5,6-tetrahydropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | Methanesulfonate | HCID 85257 | — |
| Reactant | 2-(2-Ethoxy-2-phenyl-ethenyl)-3,4,5,6-tetrahydropyridine tetrafluoroborate | HCID 86736219 | — |
| Reactant | HCID 178463269 | HCID 178463269 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | 2-[2-Phenyl-2-(diethylamino)-ethenyl]-3,4,5,6-tetrahydropyridine | HCID 53901148 | — |
Reaction Steps
Analogously to Example 1, there is obtained, starting with 9.5 g of 2-(2-ethoxy-2-phenyl-ethenyl)-3,4,5,6-tetrahydropyridine-tetrafluoroborate and 30 ml of cyclohexylamine, 2-[(2-phenyl-2-(cyclohexylamino)-ethenyl]-3,4,5,6-tetrahydropyridine, and from this its (1:1)-methanesulphonate, m.p. 172°-173°; and starting with 9.5 g of 2-(2-ethoxy-2-phenyl-ethenyl)-3,4,5,6-tetrahydropyridine-tetrafluoroborate and 30 ml of diethylamine, is obtained 2-[2-phenyl-2-(diethylamino)-ethenyl]-3,4,5,6-tetrahydropyridine, and from this its (1:1)-fumarate, m.p. 169°-170° (from isopropanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04130652 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-16d427ede03343c3b3d0734e3049c9e8 |
| Source note | uspto-grants-1978_12 |