HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → N-(4-nitrostyrylsulfonyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-(4-Nitrophenyl)ethene-1-sulfonamide | HCID 53633180 | — |
| Reactant | HCID 54565141 | HCID 54565141 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-(4-nitrostyrylsulfonyl)benzamide | HCID 54406439 | 76% |
Reaction Steps
N-(4-Nitrostyrylsulfonyl)benzimidoyl chloride. A mixture of 4-nitrostyrylsulfonamide (18.2 g., 0.08 mole), benzoyl chloride (12.6 g., 0.09 mole) and phosphorus oxychloride (13.8 g., 0.09 mole) is heated at steam bath temperature for 1.5 hr. The reaction mixture diluted with 20 ml. of ethyl acetate, cooled and filtered affords 19.0 g. (76% yield) of N-(4-nitrostyrylsulfonyl)benzamide, m.p. 192°-195° C., from ethyl acetate-hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04130663 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-e331235367b8419f903d6f7379c922d5 |
| Source note | uspto-grants-1978_12 |