3-Ethynylpyridine → 5-(4-Chloro-phenyl)-3-pyridin-3-ylethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

HRID 662181Notes

Reaction equation

HRID 662181 reaction equation
[C:22](#[CH:23])[c:24]1[cH:25][n:26][cH:27][cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[I:21])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:23]#[C:22][c:24]2[cH:25][n:26][cH:27][cH:28][cH:29]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 1860033-EthynylpyridineHCID 670008255-(4-Chloro-phenyl)-3-iodo-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 118520315-(4-Chloro-phenyl)-3-pyridin-3-ylethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

Sources & evidence

ORD record
ord-3285ea2beb0542cfba054cc3397df4d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…