Acetic Acid → HCID 70615223, compound

HRID 66224Notes

Reaction equation

HRID 66224 reaction equation
C[O:2][C:3](=[O:52])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][S:11]([C:14]2[CH:15]=[C:16]3[C:21](=[CH:22][CH:23]=2)[C:20]([S:24]([NH:27][C:28]2[CH:37]=[CH:36][C:31]([C:32]([O:34]C)=[O:33])=[CH:30][CH:29]=2)(=[O:26])=[O:25])=[CH:19][C:18]([S:38]([NH:41][C:42]2[CH:51]=[CH:50][C:45]([C:46]([O:48]C)=[O:47])=[CH:44][CH:43]=2)(=[O:40])=[O:39])=[CH:17]3)(=[O:13])=[O:12])=[CH:6][CH:5]=1.C(O)(=O)C.[OH-].[Na+:58]>C(O)C>[Na+:58].[Na+:58].[Na+:58].[C:20]1([S:24]([NH:27][C:28]2[CH:37]=[CH:36][C:31]([C:32]([O-:34])=[O:33])=[CH:30][CH:29]=2)(=[O:26])=[O:25])[C:21]2[C:16](=[CH:15][C:14]([S:11]([NH:10][C:7]3[CH:8]=[CH:9][C:4]([C:3]([O-:52])=[O:2])=[CH:5][CH:6]=3)(=[O:12])=[O:13])=[CH:23][CH:22]=2)[CH:17]=[C:18]([S:38]([NH:41][C:42]2[CH:43]=[CH:44][C:45]([C:46]([O-:48])=[O:47])=[CH:50][CH:51]=2)(=[O:40])=[O:39])[CH:19]=1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 14798Sodium HydroxideHCID 54080400HCID 54080400, compound

Product 1

HCID 70615223HCID 70615223, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 9.0 g portion of the product of Example 7 is dissolved in 46.5 ml of 2N sodium hydroxide and stirred for 45 minutes. The solution is neutralized with 2.7 ml of glacial acetic acid and diluted with 200 ml of ethanol. A yellow solid separates which is collected by filtration, washed with ethanol and ether, and dried to give 8.7 g of the product of the Example.

Workup

  1. filtrationA yellow solid separates which is collected by filtration
  2. washwashed with ethanol and ether
  3. customdried

Sources & evidence

ORD record
ord-b5bd33d821ec408681a4b714a1fd00cb
Source dataset
uspto-grants-1978_12
Patent number
US04130660

Reaction notes

Loading…