5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine → 4-(2-(3-(methylsulfonyl)phenyl)-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)thiazolo[5,4-d]pyrimidin-7-yl)morpholine

HRID 662458Notes

Reaction equation

HRID 662458 reaction equation
[CH3:27][C:28]1([CH3:29])[C:30]([CH3:31])([CH3:32])[O:33][B:34]([c:35]2[cH:36][c:37]3[c:38]([n:39][cH:40]2)[nH:41][cH:42][cH:43]3)[O:44]1.[Cl:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:11]1[cH:12][c:13]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:14][cH:15][cH:16]1)[n:10]2>>[c:2]1(-[c:35]2[cH:36][c:37]3[c:38]([n:39][cH:40]2)[nH:41][cH:42][cH:43]3)[n:3][c:4]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:11]1[cH:12][c:13]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:14][cH:15][cH:16]1)[n:10]2

Participants

3

Reactant 2

HCID 242087895-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridineHCID 866300685-Chloro-2-(3-(methylsulfonyl)phenyl)-7-morpholinothiazolo[5,4-d]pyrimidine

Product 1

HCID 252541494-(2-(3-(methylsulfonyl)phenyl)-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)thiazolo[5,4-d]pyrimidin-7-yl)morpholine

Sources & evidence

ORD record
ord-389044d08d67426db39eda976ab9f4d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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