Thionyl Chloride → 4-(2,6-Difluorobenzyloxy)benzylcarbonyl chloride

HRID 662648Notes

Reaction equation

HRID 662648 reaction equation
[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][cH:8][c:9]([CH2:12][C:13]([CH2:14][C:15]([O:16][CH2:17][CH3:18])=[O:19])=[O:20])[cH:10][cH:11]2)[c:21]([F:25])[cH:22][cH:23][cH:24]1.[S:26]([Cl:27])([Cl:28])=[O:29]>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][cH:8][c:9]([CH2:12][C:13](=[O:20])[Cl:28])[cH:10][cH:11]2)[c:21]([F:25])[cH:22][cH:23][cH:24]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 21964507Ethyl 4-(4-(2,6-difluorobenzyloxy)phenyl)-3-oxobutyrate

Product 1

HCID 219645094-(2,6-Difluorobenzyloxy)benzylcarbonyl chloride

Sources & evidence

ORD record
ord-bd836dfa579e44f1b8dd463f65fa62d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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