反应详情

A 53.6 g portion of ethyl m-chlorophenylacetate (prepared by esterification of the corresponding acid), 51.5 g of N-bromosuccinimide and one gram of benzoyl peroxide in 1.25 liters of carbon tetrachloride is stirred with a Nichrome metal stirrer and refluxed for 20 hours. The mixture is cooled, filtered and concentrated to an orange oil. Vacuum distillation yields the product ethyl α-bromo-m-chlorophenylacetate.

1. temperaturerefluxed for 20 hours
2. temperatureThe mixture is cooled
3. filtrationfiltered
4. concentrationconcentrated to an orange oil
5. distillationVacuum distillation