HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 3-(1-Adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Reactant | 1-(4-Chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 10130331 | — |
| Product | 3-(1-Adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20468354 | — |
Reaction Steps
A sample of 19.35 g of 1-p-chlorophenyl-3-azabicyclo[3.1.0]hexane, 10.59 g of sodium carbonate and 19.87 g of 1-adamantanecarboxylic acid chloride are reacted in accordance with Example 36, yielding the product 3-(1-adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane as a white solid, mp 163°-165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04131611 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-7dd1cd11db6b43f6852336020da61547 |
| Source note | uspto-grants-1978_12 |