HCID 20468400, compound → HCID 20468404, compound

HRID 66283Notes

Reaction equation

HRID 66283 reaction equation
[F:1][C:2]1[CH:21]=[CH:20][C:5]([C:6]([N:8]2[CH2:13][CH:12]3[C:10]([C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)([CH2:11]3)[CH2:9]2)=O)=[CH:4][CH:3]=1.[H-].COCCO[Al+]OCCOC.[Na+].[H-]>>[F:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:8]2[CH2:13][CH:12]3[C:10]([C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)([CH2:11]3)[CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 20468400HCID 20468400, compoundHCID 21584525Sodium bis(2-methoxyethoxy)aluminiumhydride

Product 1

HCID 20468404HCID 20468404, compound

Procedure

In a similar manner, 3-(p-fluorobenzoyl)-1-phenyl-3-azabicyclo[3.1.0]hexane is reduced by sodium bis(2-methoxyethoxy)aluminum hydride to give 3-(p-fluorobenzyl)-1-phenyl-3-azabicyclo[3.1.0]hexane.

Sources & evidence

ORD record
ord-5fac6625e7644374b3b077ac970fb406
Source dataset
uspto-grants-1978_12
Patent number
US04131611

Reaction notes

Loading…