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HRID66289

反应详情

EQUATION

反应方程式

HRID 66289 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])O
HCID944

Nitric Acid

HNO3

结构：O=C(O)C1CC1(C(=O)O)c1ccccc1
HCID12719776

1-Phenylcyclopropane-1,2-dicarboxylic acid

C11H10O4

PRODUCTS

生成物

1
结构：O=C(O)C1CC1(C(=O)O)c1ccc([N+](=O)[O-])cc1
HCID12891365

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=S(=O)(O)O
溶剂HCID1118

Sulfuric acid

H2O4S

PROCEDURE

实验过程

To a stirred slurry of 20.6 g of 1-phenylcyclopropane-1,2-dicarboxylic acid in 25 ml of concentrated sulfuric acid at 0° C. is added 15 ml of concentrated nitric acid over 30 minutes. The resultant solution is then stirred at ambient tmperature for 30 minutes and then poured onto ice. The crystalline product is recrystallized from hexane-ethyl acetate to give 1-(p-nitrophenyl)-cyclopropane-1,2-dicarboxylic acid as colorless crystals, m.p. 138°-144° C.

WORKUP

后处理

  1. additionpoured onto ice
  2. customThe crystalline product is recrystallized from hexane-ethyl acetate