4-(3-Fluorophenoxy)piperidine → 4-(Piperidin-4-yloxy)benzonitrile

HRID 662894Notes

Reaction equation

HRID 662894 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15]2)[cH:7][cH:8]1.[F:23][c:24]1[cH:25][c:26]([O:27][CH:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[cH:34][cH:35][cH:36]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:9][CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 185240024-(3-Fluorophenoxy)piperidineHCID 23019443tert-Butyl 4-(4-cyanophenoxy)piperidine-1-carboxylate

Product 1

HCID 112411094-(Piperidin-4-yloxy)benzonitrile

Sources & evidence

ORD record
ord-938f083c59ec4dcf984bc90b2e644a7c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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