Toluene → Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate
Reaction equation
[CH3:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[F:1][c:2]1[c:3]([C:9]([CH3:10])=[O:11])[cH:4][cH:5][cH:6][c:7]1[F:8].[O:12]=[C:13]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[C:19](=[O:20])[O:21][CH2:22][CH3:23]>>[F:1][c:2]1[c:3]([C:9]([CH2:10][C:13]([OH:12])([C:14](=[O:15])[O:16][CH2:17][CH3:18])[C:19](=[O:20])[O:21][CH2:22][CH3:23])=[O:11])[cH:4][cH:5][cH:6][c:7]1[F:8]Participants
4
Sources & evidence
- ORD record
- ord-28fab547802e46c9800c27bf6eea0284
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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