Acetyl chloride → HCID 20468403, compound

HRID 66294Notes

Reaction equation

HRID 66294 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]23[CH2:14][CH:13]2[CH2:12][NH:11][CH2:10]3)=[CH:5][CH:4]=1.[C:15](Cl)(=[O:17])[CH3:16]>>[C:15]([N:11]1[CH2:12][CH:13]2[C:9]([C:6]3[CH:5]=[CH:4][C:3]([Cl:2])=[CH:8][CH:7]=3)([CH2:14]2)[CH2:10]1)(=[O:17])[CH3:16]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 127198421-(4-Chlorophenyl)-3-azabicyclo[3.1.0]hexane Hydrochloride

Product 1

HCID 20468403HCID 20468403, compound

Procedure

Using the method of Example 19, 1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane (Example 1) is reacted with acetyl chloride to give 3-acetyl-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane and then is converted to 1-(p-chlorophenyl)-3-ethyl-3-azabicyclo[3.1.0]hexane which is obtained as a brown oil.

Sources & evidence

ORD record
ord-184a4aefe1bd41c792b9efe639749bc2
Source dataset
uspto-grants-1978_12
Patent number
US04131611

Reaction notes

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