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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66304Generated: October 25, 2026

4-Toluenesulfonyl chloride → 3-[2-(4-p-Toluenesulphonamido-1-piperidyl)ethyl]indole

https://huagongshe.com/reaction/66304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant3-[2-(4-Aminopiperidyl)ethyl]indole, hydrateHCID 20384353—
Product3-[2-(4-p-Toluenesulphonamido-1-piperidyl)ethyl]indoleHCID 22754842—

Reaction Steps

Using an analogous procedure to Example 1 3[2-(4-amino-1-piperidyl)ethyl]indole monohydrate may be reacted with p-toluenesulphonyl chloride to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04131680
Source datasetuspto-grants-1978_12
ORD IDord-2d3d020eed65469c976f193f30c90ee8
Source noteuspto-grants-1978_12