Azetidinecarboxylic Acid → 1-[[3-Fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl]azetidine-2-carboxylic acid

HRID 663526Notes

Reaction equation

HRID 663526 reaction equation
[F:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][cH:8][c:9]1-[c:10]1[s:11][c:12]2[n:13][c:14]([C:19]3([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[cH:15][cH:16][c:17]2[n:18]1.[NH:28]1[CH:29]([C:32](=[O:33])[OH:34])[CH2:30][CH2:31]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][N:28]2[CH:29]([C:32](=[O:33])[OH:34])[CH2:30][CH2:31]2)[cH:7][cH:8][c:9]1-[c:10]1[s:11][c:12]2[n:13][c:14]([C:19]3([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[cH:15][cH:16][c:17]2[n:18]1

Participants

3

Reactant 2

HCID 17288Azetidinecarboxylic AcidHCID 591749073-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzaldehyde

Product 1

HCID 671121221-[[3-Fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl]azetidine-2-carboxylic acid

Sources & evidence

ORD record
ord-d7bbcf2205344d70b6dac39e0e09a958
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…