2,5-Difluoronitrobenzene → N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-4-fluoro-2-nitroaniline

HRID 663532Notes

Reaction equation

HRID 663532 reaction equation
[F:1][c:2]1[c:3]([N+:9](=[O:10])[O-:11])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[NH2:12][CH2:13][CH2:14][C:15]12[CH2:16][CH2:17][CH2:18][N:19]1[CH2:20][CH2:21][CH2:22]2>>[c:2]1([NH:12][CH2:13][CH2:14][C:15]23[CH2:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][CH2:22]3)[c:3]([N+:9](=[O:10])[O-:11])[cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 677672,5-DifluoronitrobenzeneHCID 107969772-(Hexahydro-1H-pyrrolizin-7a-yl)ethanamine

Product 1

HCID 10803648N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-4-fluoro-2-nitroaniline

Sources & evidence

ORD record
ord-e1cc36ca13b6451e8e6fccb30cc9792b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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