Dichloromethane → N,N-diethyl-1-(3-ethyl-4-(2-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)hydrazinecarbonyl)cyclopentyl)methanesulfonamide

HRID 663585Notes

Reaction equation

HRID 663585 reaction equation
[CH2:22]([CH3:23])[N:24]([S:25](=[O:26])(=[O:27])[CH2:28][CH:29]1[CH2:30][CH:31]([CH2:37][CH3:38])[CH:32]([C:34](=[O:35])[OH:36])[CH2:33]1)[CH2:39][CH3:40].[Cl:65][CH2:66][Cl:67].[NH:1]([NH2:2])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2.[P-:41]([F:42])([F:43])([F:44])([F:45])([F:46])[F:47].[n:48]1([O:49][C:50]([N:51]([CH3:52])[CH3:53])=[N+:54]([CH3:55])[CH3:56])[c:57]2[n:58][cH:59][cH:60][cH:61][c:62]2[n:63][n:64]1>>[NH:1]([NH:2][C:34]([CH:32]1[CH:31]([CH2:37][CH3:38])[CH2:30][CH:29]([CH2:28][S:25]([N:24]([CH2:22][CH3:23])[CH2:39][CH3:40])(=[O:26])=[O:27])[CH2:33]1)=[O:35])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 580098102-Hydrazinyl-5-tosyl-5H-pyrrolo[2,3-b]pyrazineHCID 585578104-((N,N-diethylsulfamoyl)methyl)-2-ethylcyclopentanecarboxylic acid

Product 1

HCID 58557160N,N-diethyl-1-(3-ethyl-4-(2-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)hydrazinecarbonyl)cyclopentyl)methanesulfonamide

Sources & evidence

ORD record
ord-78a651fa9f334fcbb6a6d62784a65390
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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