HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-Benzoylamino-5-nitro-2-pyridone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 3-Amino-5-nitropyridin-2(1H)-one | HCID 22754782 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Benzoylamino-5-nitro-2-pyridone | HCID 22754767 | — |
Reaction Steps
A solution of 100 mg. of 3-amino-5-nitro-2-pyridone in 1.5 ml. of pyridine was cooled and treated with 200 mg. of benzoyl chloride. After 2 hours water was added. The oil that separated was washed with water and triturated with ether. The resultant solid was recrystallized from ethyl acetate to give 3-benzoylamino-5-nitro-2-pyridone, m.p. 267°-268° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04131677 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-c14a4005988345be85980af391aebba7 |
| Source note | uspto-grants-1978_12 |