Bromide ion → N-(2-(5-bromo-2-fluorophenyl)-4-(tert-butyldimethylsilyloxy)-3,3-difluorobutan-2-yl)-2-methylpropane-2-sulfinamide

HRID 663623Notes

Reaction equation

HRID 663623 reaction equation
[Br-:29].[Br:1][c:2]1[cH:3][cH:4][c:5]([F:28])[c:6]([C:8]([C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([F:19])[F:20])=[N:21][S:22](=[O:23])[C:24]([CH3:25])([CH3:26])[CH3:27])[cH:7]1.[CH3:30][Mg+:31].[CH3:32][CH2:33][O:34][CH2:35][CH3:36]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:28])[c:6]([C:8]([C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([F:19])[F:20])([NH:21][S:22](=[O:23])[C:24]([CH3:25])([CH3:26])[CH3:27])[CH3:30])[cH:7]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 3283Diethyl EtherHCID 86650272N-(1-(5-bromo-2-fluorophenyl)-3-(tert-butyldimethylsilyloxy)-2,2-difluoropropylidene)-2-methylpropane-2-sulfinamideHCID 178477777HCID 178477777, compound

Product 1

HCID 66666208N-(2-(5-bromo-2-fluorophenyl)-4-(tert-butyldimethylsilyloxy)-3,3-difluorobutan-2-yl)-2-methylpropane-2-sulfinamide

Sources & evidence

ORD record
ord-0cdac651240c461694b62755179fb7f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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