2-(Phenylmethyl)oxirane → 9-bromo-1'-(2-hydroxy-3-phenylpropyl)spiro[3H-benzo[h][1,4]benzoxathiine-2,4'-piperidine]-5,6-dione
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:19]([cH:20]1)[C:9]1=[C:8]([C:7](=[O:21])[C:6]2=[O:22])[S:13][CH2:12][C:11]2([O:10]1)[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]2.[CH2:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[CH:30]1[O:31][CH2:32]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:19]([cH:20]1)[C:9]1=[C:8]([C:7](=[O:21])[C:6]2=[O:22])[S:13][CH2:12][C:11]2([O:10]1)[CH2:14][CH2:15][N:16]([CH2:32][CH:30]([CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[OH:31])[CH2:17][CH2:18]2Participants
3
Sources & evidence
- ORD record
- ord-c62389bceb574944aa9759d26b61d1d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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