Potassium Cation → 6-[4-(3,3-Difluoro-2-oxo-2,3-dihydroindol-1-YL)piperidin-1-YL]pyridazine-3-carboxylic acid (3-cyclopropylpropyl)amide

HRID 663743Notes

Reaction equation

HRID 663743 reaction equation
[CH:19]1([CH2:22][CH2:23][CH2:24][NH:25][C:26](=[O:27])[c:28]2[n:29][n:30][c:31]([Cl:34])[cH:32][cH:33]2)[CH2:20][CH2:21]1.[F:1][C:2]1([F:18])[C:3](=[O:17])[N:4]([CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[K+:35].[K+:36].[O-:37][C:38]([O-:39])=[O:40].[O:41]1[CH2:42][CH2:43][O:44][CH2:45][CH2:46]1>>[F:1][C:2]1([F:18])[C:3](=[O:17])[N:4]([CH:11]2[CH2:12][CH2:13][N:14]([c:31]3[n:30][n:29][c:28]([C:26]([NH:25][CH2:24][CH2:23][CH2:22][CH:19]4[CH2:20][CH2:21]4)=[O:27])[cH:33][cH:32]3)[CH2:15][CH2:16]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 671722233,3-Difluoro-1-piperidin-4-yl-1,3-dihydroindol-2-oneHCID 860259516-Chloropyridazine-3-carboxylic acid (3-cyclopropylpropyl)amide

Product 1

HCID 671720966-[4-(3,3-Difluoro-2-oxo-2,3-dihydroindol-1-YL)piperidin-1-YL]pyridazine-3-carboxylic acid (3-cyclopropylpropyl)amide

Sources & evidence

ORD record
ord-3c86d4b2af3f479d94d4f3666f8070b2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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