Methanol → 4-Chloro-2-([(2,3-difluorophenyl)methyl]thio]-6-methoxypyrimidine

HRID 663965Notes

Reaction equation

HRID 663965 reaction equation
[CH3:22][OH:23].[Cl:1][c:2]1[n:3][c:4]([S:9][CH2:10][c:11]2[c:12]([F:18])[c:13]([F:17])[cH:14][cH:15][cH:16]2)[n:5][c:6]([Cl:8])[cH:7]1.[H-:19].[Na+:20].[OH2:21]>>[Cl:1][c:2]1[n:3][c:4]([S:9][CH2:10][c:11]2[c:12]([F:18])[c:13]([F:17])[cH:14][cH:15][cH:16]2)[n:5][c:6]([O:21][CH3:22])[cH:7]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 166653HydrideHCID 859280374,6-Dichloro-2-((2,3-difluorobenzyl)thio)pyrimidine

Product 1

HCID 866198774-Chloro-2-([(2,3-difluorophenyl)methyl]thio]-6-methoxypyrimidine

Sources & evidence

ORD record
ord-91bd0f6b3cce4b7a978428d9c055e41b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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