Ammonia → 1-[2-(Dimethylamino)ethyl]-1,4-cyclohexadiene

HRID 66398Notes

Reaction equation

HRID 66398 reaction equation
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[Li].N>C(O)C>[CH3:11][N:2]([CH3:1])[CH2:3][CH2:4][C:5]1[CH2:10][CH:9]=[CH:8][CH2:7][CH:6]=1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 25125N,N-DimethylphenylethylamineHCID 3028194Lithium

Product 1

HCID 122289201-[2-(Dimethylamino)ethyl]-1,4-cyclohexadiene

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

45 g. (0.3 moles) of the dimethylphenethylamine is reduced by treatment with 16 g. of lithium (2.3 g. atom) in 1.5 1. of ammonia and 250 ml. of ethanol according to the procedure of Example 1(a) to yield crude 1-[2-(dimethylamino)ethyl]-1,4-cyclohexadiene.

Sources & evidence

ORD record
ord-c0bc3f1de4e0455fbf87f7bcc0ff3832
Source dataset
uspto-grants-1978_12
Patent number
US04131744

Reaction notes

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