Dicyclohexylcarbodiimide → N-[4-[4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl]-3-fluorophenyl]oxolane-3-carboxamide
Reaction equation
[CH:29]1([N:30]=[C:31]=[N:32][CH:33]2[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]2)[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1.[NH2:1][c:2]1[cH:3][c:4]([F:28])[c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH:14]([C:15](=[O:16])[N:17]([CH2:18][CH3:19])[CH2:20][CH3:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1.[O:44]1[CH2:45][CH:46]([C:49](=[O:50])[OH:51])[CH2:47][CH2:48]1>>[NH:1]([c:2]1[cH:3][c:4]([F:28])[c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH:14]([C:15](=[O:16])[N:17]([CH2:18][CH3:19])[CH2:20][CH3:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1)[C:49]([CH:46]1[CH2:45][O:44][CH2:48][CH2:47]1)=[O:50]Participants
4
Sources & evidence
- ORD record
- ord-219e3918bb424d39ac17663a306ece0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…