Ethanolamine → N-(2-hydroxyethyl)-4-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methoxy]benzamide

HRID 664057Notes

Reaction equation

HRID 664057 reaction equation
[NH2:27][CH2:28][CH2:29][OH:30].[OH2:31].[OH:1][C:2]1([CH2:15][O:16][c:17]2[cH:18][cH:19][c:20]([C:21](=[O:22])[O:23][CH3:24])[cH:25][cH:26]2)[CH2:3][CH2:4][N:5]([CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1>>[OH:1][C:2]1([CH2:15][O:16][c:17]2[cH:18][cH:19][c:20]([C:21](=[O:22])[NH:27][CH2:28][CH2:29][OH:30])[cH:25][cH:26]2)[CH2:3][CH2:4][N:5]([CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 962WaterHCID 222912651-Benzyl-4-(4-methoxycarbonylphenoxymethyl)piperidin-4-ol

Product 1

HCID 14989215N-(2-hydroxyethyl)-4-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methoxy]benzamide

Sources & evidence

ORD record
ord-28fc85db43414d21a51032c6ed8c7d48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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