Piperonal → Bis(1,3-benzodioxol-5-yl)methanol

HRID 664119Notes

Reaction equation

HRID 664119 reaction equation
[Br:12][c:13]1[cH:14][c:15]2[c:16]([cH:20][cH:21]1)[O:17][CH2:18][O:19]2.[CH2:22]([Li:23])[CH2:24][CH2:25][CH3:26].[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH:10]=[O:11])[cH:9]2.[O:27]1[c:28]2[cH:29][cH:30][c:31]([CH:32]([c:33]3[cH:34][c:35]([O:36][CH3:37])[cH:38][c:39]([O:40][CH3:41])[cH:42]3)[OH:43])[cH:44][c:45]2[O:46][CH2:47][CH2:48]1>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH:10]([OH:11])[c:13]1[cH:14][c:15]3[c:16]([cH:20][cH:21]1)[O:17][CH2:18][O:19]3)[cH:9]2

Participants

5

Reactant 4

HCID 8438PiperonalHCID 758311-Bromo-3,4-(methylenedioxy)benzeneHCID 69202534(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-(3,5-dimethoxyphenyl)methanolHCID 178418339Butyllithium

Product 1

HCID 384225Bis(1,3-benzodioxol-5-yl)methanol

Sources & evidence

ORD record
ord-4ca7035cc8d044aa900575958792a4ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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