反应详情

温度

0 °C

To a stirred suspension of 2-furyllithium (prepared from n-butyllithium and furan by the procedure of J. Org. Chem., 27, 1216 (1962) in ether and hexane at -78° C is added a solution of 4-chlorobutanol [Chem. Abstr., 59, 7579F (1963)] in of ether The mixture is warmed to 0° C and treated with saturated ammonium chloride. The ether phase is washed with water and brine, dried over magnesium sulfate and potassium carbonate mixture, and concentrated to give a liquid.

1. washThe ether phase is washed with water and brine
2. dry with materialdried over magnesium sulfate and potassium carbonate mixture
3. concentrationconcentrated
4. customto give a liquid