5-Methoxynicotinic acid → N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methoxynicotinamide

HRID 664168Notes

Reaction equation

HRID 664168 reaction equation
[CH3:21][O:22][c:23]1[cH:24][c:25]([C:29](=[O:30])[OH:31])[cH:26][n:27][cH:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH2:20])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH:20][C:29]([c:25]3[cH:24][c:23]([O:22][CH3:21])[cH:28][n:27][cH:26]3)=[O:30])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 47383905-Methoxynicotinic acidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 56962001N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methoxynicotinamide

Sources & evidence

ORD record
ord-4a33f324f53f4670b3c61466751e57f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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