Formic Acid → 2-(Ethylmethylamino)-4-(1-naphthyloxy)-1-butanol

HRID 66419Notes

Reaction equation

HRID 66419 reaction equation
[CH2:1]([NH:3][CH:4]([CH2:7][CH2:8][O:9][C:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1)[CH2:5][OH:6])[CH3:2].[CH:20](O)=O>>[CH2:1]([N:3]([CH3:20])[CH:4]([CH2:7][CH2:8][O:9][C:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1)[CH2:5][OH:6])[CH3:2]

Participants

3

Reactant 2

HCID 284Formic AcidHCID 227549982-(Ethylamino)-4-(1-naphthyloxy)-1-butanol

Product 1

HCID 540539222-(Ethylmethylamino)-4-(1-naphthyloxy)-1-butanol

Procedure

2-(ethylamino)-4-(1-naphthyloxy)-1-butanol, described in Example 6, with formic acid, followed by reduction, gives 2-(ethylmethylamino)-4-(1-naphthyloxy)-1-butanol, and

Sources & evidence

ORD record
ord-db6892a97b1043438fc58f40f0628b3b
Source dataset
uspto-grants-1978_12
Patent number
US04131745

Reaction notes

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