Aluminium lithium hydride → HCID 20372149, compound

HRID 66422Notes

Reaction equation

HRID 66422 reaction equation
[CH3:1][O:2][CH2:3][CH:4]([N:18]([CH3:21])[CH:19]=O)[CH2:5][CH2:6][O:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][CH:9]=1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:1][O:2][CH2:3][CH:4]([N:18]([CH3:21])[CH3:19])[CH2:5][CH2:6][O:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 22754995N-[1-(Methoxymethyl)-3-(1-naphthyloxy)propyl]-N-methylformamide

Product 1

HCID 20372149HCID 20372149, compound

Procedure

N-[1-(Methoxymethyl)-3(1-naphthyloxy)propyl]-N-methylformamide, described in Example 8, is reduced with LiAlH4 in the manner described in Example 4 to give the title compound, nmr (CDCl3) δ 2.05 (m, 2H), 2.35 (s, 6H), 3.0 (s, 1H), 3.35 (s, 3H), 3.5 (m, 2H), 4.25 (t, J = 5.5Hz, 2H) and 6.75-8.4 (7H).

Sources & evidence

ORD record
ord-71ec2b5d4f144cb598e801857d7d3566
Source dataset
uspto-grants-1978_12
Patent number
US04131745

Reaction notes

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