Methyl iodide → 1-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine

HRID 66423Notes

Reaction equation

HRID 66423 reaction equation
[CH:1]([O:3][CH2:4][CH:5]([NH:15][CH:16]=O)[CH2:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=O.[CH3:18]I>>[CH3:1][O:3][CH2:4][CH:5]([N:15]([CH3:16])[CH3:18])[CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 54572717HCID 54572717, compound

Product 1

HCID 227550141-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine

Procedure

2-(formylamino)-4-phenoxy-1-butanol formate, described in Example 3, with methyl iodide, followed by reduction, gives 1-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine,

Sources & evidence

ORD record
ord-c73a6e7beb7f4c9eb924a4e30eddf39a
Source dataset
uspto-grants-1978_12
Patent number
US04131745

Reaction notes

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