Methyl iodide → 1-methoxy-N-ethyl-N-methyl-4-(1-naphthyloxy)-2-butanamine

HRID 66424Notes

Reaction equation

HRID 66424 reaction equation
[C:1]([O:4][CH2:5][CH:6]([NH:20][C:21](=O)[CH3:22])[CH2:7][CH2:8][O:9][C:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1)(=O)C.[CH3:24]I>>[CH3:1][O:4][CH2:5][CH:6]([N:20]([CH2:21][CH3:22])[CH3:24])[CH2:7][CH2:8][O:9][C:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 541160012-(Acetylamino)-4-(1-naphthyloxy)-1-butanol Acetate

Product 1

HCID 227549941-methoxy-N-ethyl-N-methyl-4-(1-naphthyloxy)-2-butanamine

Procedure

2-(acetylamino)-4-(1-naphthyloxy)-1-butanol acetate, described in Example 5, with methyl iodide, followed by reduction, gives 1-methoxy-N-ethyl-N-methyl-4-(1-naphthyloxy)-2-butanamine, and

Sources & evidence

ORD record
ord-2af7cf6f10a841ba998746c56930b7a3
Source dataset
uspto-grants-1978_12
Patent number
US04131745

Reaction notes

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