Cyclopentylamine → 2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-cyclopentyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

HRID 664297Notes

Reaction equation

HRID 664297 reaction equation
[CH:28]1([NH2:33])[CH2:29][CH2:30][CH2:31][CH2:32]1.[NH2:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12]([C:18](=[O:19])[OH:20])[cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12]([C:18](=[O:19])[NH:33][CH:28]4[CH2:29][CH2:30][CH2:31][CH2:32]4)[cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[n:7]1

Participants

3

Reactant 2

HCID 2906CyclopentylamineHCID 594022702-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid

Product 1

HCID 467013872-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-cyclopentyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

Sources & evidence

ORD record
ord-9d80826aa87744caa13a74b199507f95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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