Potassium Cation → 3-benzo[b]furan-2-yl-1-perhydro-2H-pyran-2-yl-1H-indazole-5-carbonitrile

HRID 664485Notes

Reaction equation

HRID 664485 reaction equation
[Br:1][c:2]1[n:3][n:4]([CH:13]2[O:14][CH2:15][CH2:16][CH2:17][CH2:18]2)[c:5]2[cH:6][cH:7][c:8]([C:11]#[N:12])[cH:9][c:10]12.[Cl:27][CH2:28][Cl:29].[K+:24].[K+:25].[K+:26].[P:19]([O-:20])([O-:21])([O-:22])=[O:23].[o:30]1[c:31]2[c:32]([cH:33][c:34]1[B:35]([OH:36])[OH:37])[cH:38][cH:39][cH:40][cH:41]2>>[c:2]1(-[c:34]2[o:30][c:31]3[c:32]([cH:33]2)[cH:38][cH:39][cH:40][cH:41]3)[n:3][n:4]([CH:13]2[O:14][CH2:15][CH2:16][CH2:17][CH2:18]2)[c:5]2[cH:6][cH:7][c:8]([C:11]#[N:12])[cH:9][c:10]12

Participants

6

Reactant 5

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 6344DichloromethaneHCID 2776266Benzo[b]furan-2-boronic acidHCID 224799453-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-5-carbonitrile

Product 1

HCID 224798583-benzo[b]furan-2-yl-1-perhydro-2H-pyran-2-yl-1H-indazole-5-carbonitrile

Sources & evidence

ORD record
ord-1d535b1eff174545af8ba97270942811
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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