HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → 1-[3-(Acetylthio)-3-(benzo[b]thien-2-ylcarbonyl)-propionyl]-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 4-(1-Benzothiophen-2-yl)-4-oxobutanoic acid | HCID 298601 | — |
| Reactant | HCID 23700354 | HCID 23700354 | — |
| Product | 1-[3-(Acetylthio)-3-(benzo[b]thien-2-ylcarbonyl)-propionyl]-L-proline | HCID 53938021 | — |
Reaction Steps
As for Example 4, γ-oxo-benzo[b]thiophene-2-butyric acid is coupled to L-proline. The coupled product is brominated and reacted with sodium thioacetate to give the product of the Example as a glass.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04342689 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-7a7d575f32724a63b5a41f895d2becde |
| Source note | uspto-grants-1982_08 |