(2-Amino-4-chloro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (4-Chloro-2-{3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:19])[cH:10][c:11]([Cl:18])[c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1)=[O:20].[C:21]([CH3:23])([CH3:24])([O:25][C:26](=[O:22])[CH2:27][C:28](=[O:29])[c:30]1[cH:31][c:32](-[c:36]2[cH:37][c:38]([CH3:43])[n:39][c:40]([CH3:42])[cH:41]2)[cH:33][cH:34][cH:35]1)[CH3:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:19][C:26](=[O:25])[CH2:27][C:28](=[O:29])[c:30]2[cH:31][c:32](-[c:36]3[cH:37][c:38]([CH3:43])[n:39][c:40]([CH3:42])[cH:41]3)[cH:33][cH:34][cH:35]2)[cH:10][c:11]([Cl:18])[c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1)=[O:20]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-1753fc7c071d4406b3a4021166a2b75b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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