HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → 1-[3-(2-thenoyl)acryloyl]-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 2-Butenoic acid, 4-oxo-4-(2-thienyl)- | HCID 3253169 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-[3-(2-thenoyl)acryloyl]-L-proline | HCID 54449391 | — |
Reaction Steps
As for Example 1, 3-(2-thenoyl)acrylic acid (0.01 mole) is coupled to L-proline (0.01 mole) with N,N'-carbonyldiimidazole (0.011 mole) in tetrahydrofuran to give 1-[3-(2-thenoyl)acryloyl]-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04342689 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-918fd92ccd3644d596e1bbc665470d06 |
| Source note | uspto-grants-1982_08 |