4-(Methylsulfonyl)benzyl Bromide → 4-chloro-N-(5,5-difluoro-2-oxoazepan-3-yl)-N-[(4-methylsulfonylphenyl)methyl]benzenesulfonamide
Reaction equation
[CH3:22][S:23](=[O:24])(=[O:25])[c:26]1[cH:27][cH:28][c:29]([CH2:30][Br:31])[cH:32][cH:33]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:30][c:29]2[cH:28][cH:27][c:26]([S:23]([CH3:22])(=[O:24])=[O:25])[cH:33][cH:32]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c59f177acfeb418b8c5576e6f132aa30
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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