Piperidin-4-ol → N-(2-chlorophenyl)-8-(4-hydroxypiperidine-1-carbonyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

HRID 665001노트

반응식

HRID 665001 반응식
[Cl:1][c:2]1[c:3]([N:8]([C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([s:28]2)-[c:15]2[c:16]([cH:20][c:21]([C:24](=[O:25])[O:26][CH3:27])[cH:22][cH:23]2)[O:17][CH2:18][CH2:19]3)[CH3:29])[cH:4][cH:5][cH:6][cH:7]1.[OH:30][CH:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1>>[Cl:1][c:2]1[c:3]([N:8]([C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([s:28]2)-[c:15]2[c:16]([cH:20][c:21]([C:24](=[O:25])[N:34]4[CH2:33][CH2:32][CH:31]([OH:30])[CH2:36][CH2:35]4)[cH:22][cH:23]2)[O:17][CH2:18][CH2:19]3)[CH3:29])[cH:4][cH:5][cH:6][cH:7]1

참가 물질

3

반응물 2

HCID 79341Piperidin-4-olHCID 442423632-[(2-Chloro-phenyl)-methyl-carbamoyl]-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-8-carboxylic acid methyl ester

생성물 1

HCID 44242708N-(2-chlorophenyl)-8-(4-hydroxypiperidine-1-carbonyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

출처 및 근거

ORD 기록
ord-8cf612b91b65482b9652c259294b6fa2
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

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