Dichloromethane → N,N,N',N'-tetramethyl 3,3'-(((3-(2-(4-(1-methylethyl)-2-thiazolyl)ethenyl)phenyl)methylene)bis(thio))-bispropanamide

HRID 665094Notes

Reaction equation

HRID 665094 reaction equation
[CH3:16][CH:17]([c:18]1[n:19][c:20]([CH:21]=[CH:22][c:23]2[cH:24][c:25]([CH:26]([S:27][CH2:28][CH2:29][C:30]([O:31][CH3:32])=[O:33])[S:34][CH2:35][CH2:36][C:37]([O:38][CH3:39])=[O:40])[cH:41][cH:42][cH:43]2)[s:44][cH:45]1)[CH3:46].[CH3:47][N:48]([C:49]([CH2:50][CH2:51][S:52][CH:53]([c:54]1[cH:55][c:56]([CH:60]=[CH:61][c:62]2[s:63][cH:64][c:65]([CH:67]([CH3:68])[CH3:69])[n:66]2)[cH:57][cH:58][cH:59]1)[S:70][CH2:71][CH2:72][C:73]([O:74][CH3:75])=[O:76])=[O:77])[CH3:78].[Cl:79][CH2:80][Cl:81].[SH:1][CH2:2][CH2:3][C:4]([O:5][CH3:6])=[O:7].[SH:8][CH2:9][CH2:10][C:11](=[O:12])[N:13]([CH3:14])[CH3:15]>>[S:8]([CH2:9][CH2:10][C:11](=[O:12])[N:13]([CH3:14])[CH3:15])[CH:53]([S:52][CH2:51][CH2:50][C:49]([N:48]([CH3:47])[CH3:78])=[O:77])[c:54]1[cH:55][c:56]([CH:60]=[CH:61][c:62]2[s:63][cH:64][c:65]([CH:67]([CH3:68])[CH3:69])[n:66]2)[cH:57][cH:58][cH:59]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 18050Methyl 3-mercaptopropionateHCID 11126302Propanamide, 3-mercapto-N,N-dimethyl-HCID 53642997Dimethyl 3,3'(((3-(2-(4-(1-methylethyl)-2-thiazolyl)ethenyl)phenyl)methylene)-bis (thio))bispropanoateHCID 54570341Methyl 3-((1-((3-dimethylamino-3-oxopropyl)thio)-1-(3-(2-(4-(1-methyl-ethyl)-2-thiazolyl)ethenyl)phenyl)methyl)thio)-propanoate

Product 1

HCID 54463992N,N,N',N'-tetramethyl 3,3'-(((3-(2-(4-(1-methylethyl)-2-thiazolyl)ethenyl)phenyl)methylene)bis(thio))-bispropanamide

Sources & evidence

ORD record
ord-1e001fdb6e554459b930755f2d35274b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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