4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)morpholine → 5-Chloro-7-morpholino-2-(6-morpholinopyridin-3-yl)thiazolo[5,4-d]pyrimidine

HRID 665139Notes

Reaction equation

HRID 665139 reaction equation
[CH3:18][C:19]1([CH3:20])[C:21]([CH3:22])([CH3:23])[O:24][B:25]([c:26]2[cH:27][cH:28][c:29]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[n:30][cH:31]2)[O:38]1.[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([I:11])[n:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:26]1[cH:27][cH:28][c:29]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[n:30][cH:31]1)[n:10]2

Participants

3

Reactant 2

HCID 27953634-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)morpholineHCID 252102844-(5-Chloro-2-iodothiazolo[5,4-d]pyrimidin-7-yl)morpholine

Product 1

HCID 866300735-Chloro-7-morpholino-2-(6-morpholinopyridin-3-yl)thiazolo[5,4-d]pyrimidine

Sources & evidence

ORD record
ord-8db0cfc32ab84489b5e83a5c14c72e0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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