Ammonium → 1,1-dimethylethyl 4-[2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl]-1-piperidinecarboxylate

HRID 665227Notes

Reaction equation

HRID 665227 reaction equation
[Br:1][c:2]1[cH:3][n:4]([CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12.[NH4+:27].[OH-:28]>>[Br:1][c:2]1[cH:3][n:4]([CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[c:5]2[n:6][cH:7][n:8][c:9]([NH2:27])[c:10]12

Participants

4

Reactant 3

HCID 223AmmoniumHCID 961HydroxideHCID 866636851,1-dimethylethyl 4-[2-(5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl]-1-piperidinecarboxylate

Product 1

HCID 668239481,1-dimethylethyl 4-[2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl]-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-e303a563cd104f61acff7be60deaffc3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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