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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 665290Generated: October 25, 2026

Diisopropylamine → 4,4,4-Trifluoro-3-hydroxy-3-methyl-1-[4-(pyrid-4-ylsulfonyl)phenyl]but-1-yne

https://huagongshe.com/reaction/665290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantMethyl trifluoromethyl ketoneHCID 9871—
Reactant4-(4-Pyridylsulfonyl)phenylacetyleneHCID 19939304—
ReactantButyllithiumHCID 178418339—
Product4,4,4-Trifluoro-3-hydroxy-3-methyl-1-[4-(pyrid-4-ylsulfonyl)phenyl]but-1-yneHCID 19939315—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-23330c99bad445e9a08f0b6676401a02
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)