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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66532Generated: October 28, 2026

L-Proline → HCID 54203320, compound

https://huagongshe.com/reaction/66532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlineHCID 145742—
ReactantIndole-3-(4'-oxo)butyric acidHCID 730037—
ProductHCID 54203320HCID 54203320—

Reaction Steps

As for Example 1, 4-oxo-4-(3-indolyl)butyric acid (0.1 mole) is coupled to L-proline to give 1-[3-(3-indolylcarbonyl)propionyl]-L-proline. The preceding compound is reacted with bromine in acetic acid and the brominated derivative is reacted with sodium thioacetate in acetonitrile to give the product of the Example as a glass.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04342691
Source datasetuspto-grants-1982_08
ORD IDord-9c7f04a7ab314c66a91c079c67c92e01
Source noteuspto-grants-1982_08