Formaldehyde → 3-(6-Methoxynaphthalen-2-yl)-9-methyl-3,9-diazaspiro[5.5]undecane

HRID 665341Notes

Reaction equation

HRID 665341 reaction equation
[C:26]([O:27][BH-:28]([O:29][C:30](=[O:31])[CH3:32])[O:33][C:34](=[O:35])[CH3:36])(=[O:37])[CH3:38].[CH2:24]=[O:25].[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([N:13]3[CH2:14][CH2:15][C:16]4([CH2:17][CH2:18]3)[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]4)[cH:9][c:10]2[cH:11][cH:12]1.[Cl:40][CH:41]([Cl:42])[CH3:43].[Na+:39]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([N:13]3[CH2:14][CH2:15][C:16]4([CH2:17][CH2:18]3)[CH2:19][CH2:20][N:21]([CH3:26])[CH2:22][CH2:23]4)[cH:9][c:10]2[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 712FormaldehydeHCID 923Sodium ionHCID 63651,1-DichloroethaneHCID 2724942TriacetoxyborohydrideHCID 119845943,9-Diazaspiro[5.5]undecane, 3-(6-methoxy-2-naphthalenyl)-

Product 1

HCID 159408093-(6-Methoxynaphthalen-2-yl)-9-methyl-3,9-diazaspiro[5.5]undecane

Sources & evidence

ORD record
ord-b173b4e3eccd4b0ba0836286b3c91d97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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