Water → 2-[2'-(3-Methoxypropyl)-3-methylbiphenyl-4-yl]-3-pyridin-3-ylpropanenitrile

HRID 665554Notes

Reaction equation

HRID 665554 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:18])[c:5]([CH:8]([C:9]#[N:10])[CH2:11][c:12]2[cH:13][n:14][cH:15][cH:16][cH:17]2)[cH:6][cH:7]1.[CH3:19][O:20][CH2:21][CH2:22][CH2:23][c:24]1[c:25]([B:30]([OH:31])[OH:32])[cH:26][cH:27][cH:28][cH:29]1.[CH3:33][O:34][CH2:35][CH2:36][O:37][CH3:38].[OH2:39]>>[c:2]1(-[c:25]2[c:24]([CH2:23][CH2:22][CH2:21][O:20][CH3:19])[cH:29][cH:28][cH:27][cH:26]2)[cH:3][c:4]([CH3:18])[c:5]([CH:8]([C:9]#[N:10])[CH2:11][c:12]2[cH:13][n:14][cH:15][cH:16][cH:17]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 58083347[2-(3-Methoxypropyl)phenyl]boronic acidHCID 674455322-(4-Bromo-2-methylphenyl)-3-pyridin-3-ylpropanenitrile

Product 1

HCID 674474272-[2'-(3-Methoxypropyl)-3-methylbiphenyl-4-yl]-3-pyridin-3-ylpropanenitrile

Sources & evidence

ORD record
ord-572b3eecdf8a4a37b8ff5dd8b50c6683
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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